- Title
- Quality microbiological diagnostics and antimicrobial susceptibility testing, an essential component of antimicrobial resistance surveillance and control efforts in Pacific island nations
- Creator
- Ferguson, John Kenneth; Joseph, Joseph; Kangapu, Samson; Zoleveke, Hilda; Townell, Nicola; Duke, Trevor; Manning, Laurens; Lavu, Evelyn
- Relation
- Western Pacific Surveillance and Response Journal Vol. 11, Issue 1, p. 41-46
- Publisher Link
- http://dx.doi.org/10.5365/wpsar.2018.9.3.004
- Publisher
- World Health Organization, Regional Office for the Western Pacific
- Resource Type
- journal article
- Date
- 2020
- Description
- Problem: Emerging bacterial antimicrobial (antibiotic) resistance (AMR) is a global threat to human health. However, most lower income countries do not have microbiological diagnostic testing for prompt, reliable confirmation of bloodstream infection and identification of AMR. Context: Clinicians in Pacific island nations are increasingly challenged by patients who have infection due to antimicrobial-resistant bacteria. Treatment of infection remains empirical because of a lack of diagnostic testing capacity and may follow guidelines that were formulated without reference to local measures of AMR prevalence. There is limited understanding among clinicians of microbiology testing and test interpretation. Action: Examine the lessons learnt from pilot laboratory development programmes in two Pacific island nations that focused on establishing standard procedures for micrological diagnostics and antimicrobial susceptibility testing (AST) and on improving the training of clinicians to increase their use of laboratory services. Outcome: The pilot programmes addressed a range of logistical difficulties and evaluated two blood culture systems. They also examined and improved internal QC implementation and evaluated the prevalence of AMR. Discussion: Continued development of microbiological diagnostic capability in the Pacific region is paramount. Pacific Island nations need to develop the capability of at least one central laboratory to culture AMR pathogens and subject them to quality-controlled AST or arrange for suitable referral to a nearby country.
- Subject
- diagnostic techniques; antimicrobial; emerging bacterial; resistance
- Identifier
- http://hdl.handle.net/1959.13/1457007
- Identifier
- uon:45286
- Identifier
- ISSN:2094-7321
- Rights
- This work is licensed under a Creative Commons Attribution IGO License. For more information, see (http://creativecommons.org/licenses/by/3.0/igo/legalcode)
- Language
- eng
- Full Text
- Reviewed
- Hits: 2572
- Visitors: 2661
- Downloads: 118
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT02 | Publisher version (open access) | 273 KB | Adobe Acrobat PDF | View Details Download |